Path B - Module 54: Final Project: Rational Enzyme Engineering#

You are now a Master. Your final task is to design a thermostable PETase variant from its sequence, verify its fold, and simulate its interaction with a plastic monomer.

  1. Load 6EQE and Repair it.

  2. Mutate I179F and introduce the Disulfide bridge (S238C/A289C).

  3. Build the BHET substrate.

  4. Solvate and Minimize the system.

  5. Measure the Buried Area of the interface.

The future of sustainable plastic recycling is in your hands.

import molsysmt as msm
print("Path B Final Project Template Ready.")